Comprehensive meta analysis subgroup within thea nalysis
Reliable data on the burden of foodborne illness due to consumer mishandling of food prepared and consumed in domestic households is not routinely and consistently collected and reported in many countries. In Canada, approximately 4 million cases of foodborne illness occur each year, with acute gastroenteritis estimated to cost $3.7 billion annually.
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In addition, 14 major foodborne pathogens are estimated to cause US$14.0 billion and a loss of 61,000 quality-adjusted life years annually. For example, an estimated 48 million cases of foodborne illness occur each year in the United States (US), causing approximately 128,000 hospitalizations and 3000 deaths. Future research in this area is needed using more robust experimental designs to build on interventions shown to be effective in uncontrolled before-and-after studies.įoodborne illness has a large public health and economic burden worldwide. In controlled trials, food safety education interventions showed significant effects in some contexts however, many outcomes were very heterogeneous and do not provide a strong quality of evidence to support decision-making. Some variation in outcomes was explained in meta-regression models, including a dose effect for behaviour outcomes in RCTs. Uncontrolled before-and-after study outcomes were very heterogeneous and we have little confidence that the meta-analysis results reflect the true effect. We identified a moderate to high confidence in results from two large RCTs investigating community- and school-based educational training interventions on behaviour outcomes in children and youth (median standardized mean difference = 0.20, range: 0.05, 0.35) in two small RCTs evaluating video and written instructional messaging on behavioural intentions in adults (SMD = 0.36, 95 % confidence interval : 0.02, 0.69) and in two NRT studies for university-based education on attitudes of students and staff (SMD = 0.26, 95 % CI: 0.10, 0.43). blinding), with some high risk-of-bias ratings due to incomplete outcome data and selective reporting. Several studies did not provide sufficient details on key design features (e.g. We identified 79 relevant studies: 17 randomized controlled trials (RCTs) 12 non-randomized controlled trials (NRTs) and 50 uncontrolled before-and-after studies. Meta-regression was conducted where appropriate to identify possible sources of between-trial heterogeneity. Meta-analysis was conducted on data subgroups stratified by key study design-intervention-population-outcome categories and subgroups were assessed for their quality of evidence. Experimental studies conducted in developed countries were prioritized for risk-of-bias assessment and data extraction.
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#Comprehensive meta analysis subgroup within thea nalysis verification#
Relevant articles were identified through a preliminary scoping review that included: a comprehensive search in 10 bibliographic databases with verification relevance screening of abstracts and extraction of article characteristics. We conducted a systematic review and targeted meta-analyses to investigate the effectiveness of food safety education interventions for consumers. Educational interventions are necessary to improve consumer food safety practices and reduce the associated burden of foodborne illness. Foodborne illness has a large public health and economic burden worldwide, and many cases are associated with food handled and prepared at home.